Search Advanced
2005 Volume 14 Issue 11
Article Contents
Previous Article Next Article

Qian Jun, XiePing, Dou Shuo-Xing, Wang Peng-Ye. 2005: Numerical study of the coupling between F0 with varied numbers of c-subunits and F1 in an ATP synthase, Chinese Physics B, 14(11): 2214-2221.
Citation: Qian Jun, XiePing, Dou Shuo-Xing, Wang Peng-Ye. 2005: Numerical study of the coupling between F0 with varied numbers of c-subunits and F1 in an ATP synthase, Chinese Physics B, 14(11): 2214-2221.
shu

Numerical study of the coupling between F0 with varied numbers of c-subunits and F1 in an ATP synthase

  • Laboratory of Soft Matter Physics,Beijing National Laboratory for Condensed Matter Physics,Institute of Physics,Chinese Academy of Sciences,Beijing 100080,China

  • Available Online: 30/11/2005
  • Fund Project: the National Natural Science Foundation of China (Grant 60025516 and 10334100)
  • ATP synthase is a rotary motor which is composed of two portions: the ‘rotor' F0, consisting of a c-ring, and the ‘stator' F1, consisting of an α3β3 hexamer. In different species, the number of c-subunits which form the c-ring is varied from 10 to 14, whereas the α3β3 hexamer is fixed to be 3-fold symmetrical. We have numerically studied the rotational coupling between F0 with varied number of c-subunits and F1. It is found that, for any number of c-subunits,the rotor F0 advances 3 steps per revolution on average, which is determined by the period of F1, whereas the exact angular pausing positions are determined by the period of F0. When the symmetry of the c-ring of F0 is matched with the 3-fold symmetry of F1, the three steps have equivalent sizes. If not matched, the three steps become nonequivalent:both the step size and average dwell time are different for these steps.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Export Citation
PDF
XML

Article Metrics

Article views(95) PDF downloads(0) Cited by(0)

Access History

Numerical study of the coupling between F0 with varied numbers of c-subunits and F1 in an ATP synthase

  • Available Online: 30/11/2005

Abstract: ATP synthase is a rotary motor which is composed of two portions: the ‘rotor' F0, consisting of a c-ring, and the ‘stator' F1, consisting of an α3β3 hexamer. In different species, the number of c-subunits which form the c-ring is varied from 10 to 14, whereas the α3β3 hexamer is fixed to be 3-fold symmetrical. We have numerically studied the rotational coupling between F0 with varied number of c-subunits and F1. It is found that, for any number of c-subunits,the rotor F0 advances 3 steps per revolution on average, which is determined by the period of F1, whereas the exact angular pausing positions are determined by the period of F0. When the symmetry of the c-ring of F0 is matched with the 3-fold symmetry of F1, the three steps have equivalent sizes. If not matched, the three steps become nonequivalent:both the step size and average dwell time are different for these steps.

    HTML

Reference (0)

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return